The relationship between obesity and insulin resistance
Recently, insulin resistance has been heard of more and more often, with overweight and unhealthy lifestyle being implicated in its development. If you have any doubts, feel that you may be affected by this illness and then visit our diabetologist at our newly opened Swiss Premium Medical Center! In August and September you will receive a 20% discount from the fee of the first consultation.
Insulin is produced by pancreatic beta cells. Carbohydrates broken down in the stomach and intestines are transferred to the blood stream, where cells absorb glucose with the help of the insulin and use it in the form of energy, for example in the liver or muscles. Insulin resistance is expressed when the body produces insulin, but cannot effectively use it. In case of inadequate insulin production, cells cannot absorb glucose from the blood, resulting in a higher blood glucose level, which leads later to the development of pre-diabetes (a condition where blood sugar levels are higher than normal but not yet high enough to diagnose diabetes) or diabetes.
This condition is usually asymptomatic for years, so the screening is most important at this stage because early detection and lifestyle change can reverse the pre-diabetes and delay the development of diabetes. The screening is usually performed with OGTT (oral glucose tolerance test).
In insulin resistance, muscle, fat, and liver cells do not provide adequate insulin response, so more insulin production will be required, which may eventually lead to the exhaustion of beta cells.
In the development of insulin resistance, obesity, especially abdominal obesity, poses an increased risk. Additional risk factors:
- sedentary lifestyle,
- delivering newborns over 4500 gr,
- diabetes in the family,
- gestational diabetes,
- PCOS (polycystic ovary disease),
- heart disease
- high cholesterol level
As insulin resistance and pre-diabetes can be reversed, it is very important to change our lifestyle in a timely manner, weight loss, exercise (combination of aerobic and anaerobic exercises several times a week), smoking cessation and the implementation of a so-called Mediterranean diet are suggested.
Studies have shown that even a few percent weight loss lowers the chances of developing diabetes with eve 50-60%. Make an appointment for counselling, consultation at +36 1 225 0566!